Ferulsinaic acid, a sesquiterpene coumarin with a rare carbon skeleton from Ferula species.
نویسندگان
چکیده
Fractionation of methylene chloride extracts of the resin of Ferula vesceritensis and F. sinaica afforded three sesquiterpene coumarins and a glucose derivative. One of them was a sesquiterpene with a rare carbon skeleton. The structures of these compounds were determined by extensive NMR studies, including DEPT, COSY, NOE, HMQC, and HMBC.
منابع مشابه
Two New Sesquiterpene Coumarins, Ferusinol and Samarcandin Diastereomer, from Ferula sinaica
Re-investigation of the methylene chloride extract of the roots of Ferula sinaica gave ferusinol, a new sesquiterpene coumarin with a rare carbon skeleton, and samarcandin diastereomer. The structures elucidation were determined by MS, 1H- 13C-1D and 2D NMR spectral data.
متن کاملTwo New Sesquiterpene Coumarins, Ferusinol and Samarcandin Diastereomer, from Ferula sinaica
Re-investigation of the methylene chloride extract of the roots of Ferula sinaica gave ferusinol, a new sesquiterpene coumarin with a rare carbon skeleton, and samarcandin diastereomer. The structures elucidation were determined by MS, 1H- 13C-1D and 2D NMR spectral data.
متن کاملNew sesquiterpene coumarin from the roots of Ferula latisecta
Objective: The genus of Ferula belongs to the tribe Peucedaneae, subfamily of Apioideae and family of Umbelliferae with 133 species distributed throughout the Mediterranean area and central Asia, especially in the former USSR and neighboring countries such as Iran. The popular Persian name of the most of these species is “Koma”. In this research we tried to isolate and elucidate the structure o...
متن کاملNew sesquiterpene coumarin from the roots of Ferula latisecta
OBJECTIVE The genus of Ferula belongs to the tribe Peucedaneae, subfamily of Apioideae and family of Umbelliferae with 133 species distributed throughout the Mediterranean area and central Asia, especially in the former USSR and neighboring countries such as Iran. The popular Persian name of the most of these species is "Koma". In this research we tried to isolate and elucidate the structure of...
متن کاملEffect Of Galbanic Acid, A Sesquiterpene Coumarin From Ferula Szowitsiana, As An Inhibitor Of Efflux Mechanism In Resistant Clinical Isolates Of Staphylococcus Aureus
Galbanic acid, a sesquiterpene coumarin from Ferula szowitsiana roots, was investigated for its potentiating effect on the antimicrobial activity of antibiotics as well as ethidium bromide, in 6 multidrug resistance (MDR) clinical isolates of Staphylococcus aureus. Galbanic acid had inhibitory effect on none of the isolated bacteria tested (up to 800 μg /ml). The MIC range of ciprofloxacin, tet...
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ورودعنوان ژورنال:
- Phytochemistry
دوره 68 5 شماره
صفحات -
تاریخ انتشار 2007